Author

Aspram Minasyan

Centre Hospitalier Universitaire VaudoisORCID 0000-0002-0063-2513Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

David BarrasiD· 3 shared Denarda Dangaj LanitiiD· 3 shared Bovannak Stewen ChapiD· 2 shared Eleonora GhisoniiD· 2 shared Fabrizio BenedettiiD· 2 shared Flavia De Carlo· 2 shared George CoukosiD· 2 shared Jose Ramon Conejo-GarciaiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

David BarrasORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintMar 30, 2026

Actionable spatial prostanoid barriers constrain BiTE-driven adoptive T cell immunity in intact human tumors

Bovannak Stewen Chap, Tania Santoro, Paris Kosti…·Denarda Dangaj Laniti

The paper uses patient-derived explants to study BiTE-driven T cell responses in tumors, identifying the COX/PGE2 axis as a barrier to immune activation and showing COX inhibition enhances anti-tumor effects.

DOI 10.64898/2026.03.26.713601

humanspatial transcriptomics

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ImmunologyCancer CellPeer-reviewedJul 31, 2025

Myeloid cell networks determine reinstatement of original immune environments in recurrent ovarian cancer

Eleonora Ghisoni, Fabrizio Benedetti, Aspram Minasyan…·Denarda Dangaj Laniti

The paper identifies immune phenotypes and myeloid cell networks in recurrent ovarian cancer that influence prognosis and immune environment reinstatement.

41 citationstop 1%

humanscRNA-seq

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Cancer BiologybioRxivPreprintFeb 8, 2025

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2ALow tumors via increased macrophage phagocytosis

Raquel Buj, Aidan R. Cole, Jeff Danielson…·Katherine M. Aird

This study shows that zinc availability in the tumor microenvironment affects anti-PD1 therapy response in CDKN2A-low tumors through macrophage phagocytosis.

3 citations

mouseproteomics

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