Author

Nathan Harris

Brandeis University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 5

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Organism:C. elegans· 5 Research Focus:differential expression· 4 Approach:experimental assay· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Piali SenguptaiD· 5 shared Samuel G. BatesiD· 2 shared Stephen NurrishiD· 2 shared Anders LindbergiD· 1 shared Asuka TakeishiiD· 1 shared Francesco A Servello· 1 shared Jamie M. Stonemetz· 1 shared Javier ApfeldiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersNeuroscience

Piali SenguptaORCID

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5 papers

Recent·Most cited

A repressive regulatory cascade shapes temporal patterning of activity-regulated gene expression in a defined sensory neuron type

Samuel G. Bates, Nathan Harris, Stephen Nurrish, Piali Sengupta

TRAP-seq of C. elegans AFD neurons reveals three temperature-duration expression modules; CREB-driven RCAN-1 acts in parallel with MEF-2 to repress premature expression of a delayed gene, ins-39.

bioRxiv · Jul 29, 2026 · PreprintNeuroscience✦ In-depth digest

Experience-dependent reconfiguration of receptors at a sensory compartment regulates neuronal plasticity

Nathan Harris, Priya Dutta, Nikhila Krishnan, Stephen Nurrish, Piali Sengupta

The paper shows temperature experience modulates transcription and trafficking of thermoreceptors in C. elegans AFD neurons to regulate response plasticity.

bioRxiv · Aug 13, 2025 · PreprintNeuroscience

Molecular encoding of stimulus features in a single sensory neuron type enables neuronal and behavioral plasticity

Nathan Harris, Samuel G. Bates, Zihao Zhuang, Matthew Bernstein, Jamie M. Stonemetz, Tyler J. Hill, Yanxun V. Yu, John A. Calarco, Piali Sengupta

The paper identifies how temperature stimuli are encoded in the gene expression of C. elegans thermosensory neurons, revealing transcriptional dynamics that drive plasticity.

Current Biology · Mar 27, 2023Peer-reviewedNeuroscience

Neuronal temperature perception induces specific defenses that enable C. elegans to cope with the enhanced reactivity of hydrogen peroxide at high temperature

Francesco A Servello, Rute Fernandes, Matthias Eder, Nathan Harris, Olivier M. F. Martin, Natasha Oswal, Anders Lindberg, Nohelly Derosiers, Piali Sengupta, Nicholas Stroustrup, Javier Apfeld

This study shows C. elegans uses temperature-sensing neurons to preemptively activate defenses against hydrogen peroxide, which becomes more reactive at higher temperatures.

eLife · Oct 13, 2022Peer-reviewedNeuroscience

Feeding state functionally reconfigures a sensory circuit to drive thermosensory behavioral plasticity

Asuka Takeishi, Jihye Yeon, Nathan Harris, Wenxing Yang, Piali Sengupta

The paper shows that feeding state modulates a sensory circuit in C. elegans to alter thermotaxis behavior through gut-brain signaling.

eLife · Oct 19, 2020Peer-reviewedNeuroscience