Author

Francine Padonou

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Matthieu GiraudiD· 2 shared Axel You· 1 shared C. Guyon· 1 shared Christophe Blanchet· 1 shared Claire UsaliD· 1 shared Cloé ZamitiD· 1 shared David E. RootiD· 1 shared Fanny CoulpieriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Matthieu GiraudORCID

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2 papers

Recent·Most cited

Cross-species chromatin accessibility pinpoints HIVEP3 as a driver of thymic epithelial maturation and self-antigen expression, preventing chronic inflammation

Sümeyye Yayilkan, Marie Massoda, Séverine Ménoret, Axel You, Lucas Brusselle, Claire Usal, Laurent Tesson, Mathieu Rouel, Flore Couzy, Francine Padonou, Cloé Zamit, Jérémy C. Santamaria, Pierre Maminirina, Olivier Baron, Jérôme Jullien, , Matthieu Giraud

This study identifies HIVEP3 as a critical regulator of thymic epithelial maturation and self-antigen expression, with its deficiency causing chronic inflammation.

bioRxiv · Jun 19, 2026 · PreprintImmunology

Aire-dependent genes undergo Clp1-mediated 3’UTR shortening associated with higher transcript stability in the thymus

C. Guyon, Nada Jmari, Francine Padonou, Yen-Chin Li, Olga Ucar, Noriyuki Fujikado, Fanny Coulpier, Christophe Blanchet, David E. Root, Matthieu Giraud

The paper identifies Clp1-mediated 3’UTR shortening as a post-transcriptional mechanism enhancing transcript stability of Aire-sensitive genes in thymic medullary epithelial cells.

eLife · Apr 27, 2020Peer-reviewedGenomics