Fred Zhangzhi Peng

This study designs epitope-focused immunogens targeting conserved coronavirus regions, showing broad neutralizing activity and protection in mice against diverse coronaviruses.

AptaBLE is a deep learning framework that predicts aptamer-protein binding and generates novel aptamers with high specificity and low Kd values.

This paper introduces PTM-Mamba, a protein language model that incorporates PTM tokens and Mamba blocks to improve performance on PTM-specific tasks.

EvoFlow-RNA generates and represents non-coding RNA using a masked discrete diffusion model, outperforming existing models on RNA function tasks.