Author

G. A. Duncan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 2 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. Song· 5 shared M. A. Scull· 4 shared E. Iverson· 3 shared L. Kaler· 2 shared S. Bader· 2 shared T. B. Gagliardi· 2 shared Y. Cheema· 2 shared A. Boboltz· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersBioengineering

D. Song

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Synthetic mucus barrier arrays as a nanoparticle formulation screening platform

H. Zou, A. Boboltz, Y. Cheema, D. Song, G. A. Duncan

This paper develops a synthetic mucus barrier array platform for high-throughput screening of nanoparticle formulations to improve mucosal drug delivery.

bioRxiv · Nov 29, 2023Bioengineering

Female reproductive fluid composition differs based on mating system in Peromyscus mice

K. A. Hook, C. Liu, K. A. Joyner, G. A. Duncan, H. Fisher

The paper compares fluid viscosity, pH, and calcium concentration in the reproductive tracts of polyandrous and monogamous Peromyscus mice to assess post-copulatory sexual selection effects.

bioRxiv · Mar 18, 2022 · PreprintEvolutionary Biology

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium

D. Song, E. Iverson, L. Kaler, M. A. Scull, G. A. Duncan

The paper investigates the roles of MUC5B and MUC5AC in mucociliary clearance using KO models and finds impaired transport when either mucin is absent.

bioRxiv · Mar 11, 2022Physiology

Shaping nanoparticle diffusion through biological barriers to drug delivery

B. J. Lee, Y. Cheema, S. Bader, G. A. Duncan

This study investigates how the shape of rod-shaped nanoparticles affects their diffusion through biological gels and identifies optimal dimensions for enhanced diffusion.

bioRxiv · Jul 21, 2021Bioengineering

Rhinovirus C replication is associated with the endoplasmic reticulum and triggers cytopathic effects in an in vitro model of human airway epithelium

T. B. Gagliardi, M. E. Goldstein, D. Song, K. M. Gray, J. W. Jung, K. M. Stroka, G. A. Duncan, M. A. Scull

This study investigates RV-C15 replication in human airway epithelium, identifying the endoplasmic reticulum as the primary replication site and revealing cytopathic effects on epithelial function.

bioRxiv · Apr 16, 2021Microbiology

Membrane-Tethered Mucin 1 is Stimulated by Interferon in Multiple Cell Types and Antagonizes Influenza A Virus Infection in Human Airway Epithelium

E. Iverson, K. Griswold, D. Song, T. B. Gagliardi, K. Hamidzadeh, M. Kesimer, S. Sinha, M. Perry, G. A. Duncan, M. A. Scull

This study investigates how MUC1 interacts with influenza A virus in human airway epithelium and shows that MUC1 expression increases during infection, potentially limiting viral spread.

bioRxiv · Mar 11, 2021 · PreprintMicrobiology

Modeling airway dysfunction in asthma using synthetic mucus biomaterials

D. Song, E. Iverson, L. Kaler, S. Bader, M. A. Scull, G. A. Duncan

This paper develops a synthetic mucus biomaterial to model asthma-related airway dysfunction and shows it mimics key properties of native mucus in health and disease.

bioRxiv · Oct 16, 2020Bioengineering