Sensitivity of BA.2.86 to prevailing neutralising antibody responses
D. J. Sheward, Y. Yang, M. Westerberg…·B. Murrell
This study assesses BA.2.86's sensitivity to neutralising antibodies using monoclonal antibodies and serum samples from Stockholm.
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8 papers
Recent·Most cited
D. J. Sheward, Y. Yang, M. Westerberg…·B. Murrell
This study assesses BA.2.86's sensitivity to neutralising antibodies using monoclonal antibodies and serum samples from Stockholm.
D. J. Sheward, C. Kim, J. Fischbach…·B. Murrell
The paper evaluates neutralisation resistance of Omicron sublineages BA.2.75.2, BA.4.6, and BA.2.10.4, finding BA.2.75.2 shows extensive escape from neutralising antibodies.
M. Corcoran, M. Chernyshev, M. Mandolesi…·G. B. Karlsson Hedestam
The paper identifies novel TCR alleles and Neanderthal-derived variants in modern humans, showing population-specific variation in TCR genes.
D. J. Sheward, C. Kim, J. Fischbach…·B. Murrell
This study evaluates the neutralization sensitivity of the SARS-CoV-2 BA.2.75 sublineage to monoclonal antibodies and sera from individuals infected with earlier variants.
D. J. Sheward, P. Pushparaj, H. Das…·B. M. Hällberg
The paper identifies affinity-matured antibodies that neutralize SARS-CoV-2 Omicron with high potency and resolves their structure to explain cross-neutralization.
D. J. Sheward, C. Kim, R. A. Ehling…·B. Murrell
This study assesses neutralizing antibody responses against the SARS-CoV-2 Omicron variant, showing reduced potency compared to the pandemic founder but with some cross-neutralizing capacity in vaccinated individuals.
S. Aljedani, T. J. Liban, K. Tran…·M. Pancera
The paper analyzes monoclonal antibodies from vaccinated non-human primates to identify a conserved immunodominant epitope in HIV-1 Env and how different lineages target it for potent neutralization.
M. Mandolesi, D. J. Sheward, L. Hanke…·B. Murrell
This study shows that SARS-CoV-2 spike protein subunit vaccines induce strong neutralizing antibodies in mice and macaques, with high titers after a single dose or dose-sparing regimen.