Author

M. Mandolesi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Murrell· 2 shared C. Kim· 2 shared D. J. Sheward· 2 shared G. B. Karlsson Hedestam· 2 shared J. M. Coquet· 2 shared L. Hanke· 2 shared L. Perez Vidakovics· 2 shared X. Castro Dopico· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

B. Murrell

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Author profile →

3 papers

Recent·Most cited

Archaic humans have contributed to large-scale variation in modern human T cell receptor genes

M. Corcoran, M. Chernyshev, M. Mandolesi, S. Narang, M. Kaduk, C. Sundling, A. Farnet, C. Bernhardsson, M. Larena, M. Jakobsson, G. B. Karlsson Hedestam

The paper identifies novel TCR alleles and Neanderthal-derived variants in modern humans, showing population-specific variation in TCR genes.

bioRxiv · Aug 25, 2022Immunology

Driving potent neutralization of a SARS-CoV-2 Variant of Concern with a heterotypic boost

D. J. Sheward, M. Mandolesi, E. Urgard, C. Kim, L. Hanke, L. Perez Vidakovics, A. Pankow, N. L. Smith, X. Castro Dopico, G. M. McInerney, J. M. Coquet, G. Karlsson Hedestam, B. Murrell

A single dose of a VOC-derived RBD protein boost enhances potent neutralizing antibodies against both Wu-Hu-1 and the VOC in previously vaccinated rhesus macaques.

bioRxiv · Apr 3, 2021 · PreprintImmunology

SARS-CoV-2 protein subunit vaccination elicits potent neutralizing antibody responses

M. Mandolesi, D. J. Sheward, L. Hanke, J. Ma, P. Pushparaj, L. Perez Vidakovics, C. Kim, K. Lore, X. Castro Dopico, J. M. Coquet, G. McInerney, G. B. Karlsson Hedestam, B. Murrell

This study shows that SARS-CoV-2 spike protein subunit vaccines induce strong neutralizing antibodies in mice and macaques, with high titers after a single dose or dose-sparing regimen.

bioRxiv · Jul 31, 2020Immunology