G. Charbon

Robust control of replication initiation in the absence of DnaA-ATP {leftrightharpoons} DnaA-ADP regulatory elements in Escherichia coli

The paper investigates the role of DnaA-ATP/ADP conversion in E. coli replication initiation, finding that intrinsic ATPase activity alone can maintain robust initiation, with regulatory elements enhancing stability during multifork replication.

Activation of the Cpx-envelope stress response system promotes tolerance to antibacterials delivered by arginine-rich peptides and aminoglycosides in Escherichia coli

The paper shows that Escherichia coli resistance to arginine-rich CPP-PNA conjugates involves the constitutively active Cpx-envelope stress response system, which reduces membrane potential and increases tolerance to aminoglycosides.