Author

G. D. Keppeke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

C.-C. Chang· 1 shared J. Zhong· 1 shared J.-L. Liu· 1 shared K. Gomes· 1 shared L. Diogenes· 1 shared L. E. C. Andrade· 1 shared L.-Y. Sung· 1 shared M. Peng· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

C.-C. Chang

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2 papers

Recent·Most cited

ImmunologybioRxivOct 29, 2022

''UNTARGETING'' AUTOANTIBODIES USING GENOME EDITING, A PROOF-OF-CONCEPT STUDY

G. D. Keppeke, L. Diogenes, K. Gomes, L. E. C. Andrade

This study uses CRISPR/Cas9 to knockout autoantibody-producing B-cell clones in vitro, significantly reducing antibody secretion and antigen reactivity.

DOI 10.1016/j.clim.2023.109343

humanproteomics

Cell BiologybioRxivMar 15, 2022

Molecular Crowding Facilitates Bundling of IMPDH Polymers and Cytoophidium Formation

C.-C. Chang, M. Peng, J. Zhong…·J.-L. Liu

This study shows that molecular crowding promotes IMPDH polymer bundling and cytoophidium formation, with implications for protein stability and subcellular compartment function.

DOI 10.1007/s00018-022-04448-2

humanprotein structure