Author

G. E. Thompson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. M. Hummel· 2 shared D. E. Jenne· 2 shared D. Emerling· 2 shared M. Casal Moura· 2 shared U. Specks· 2 shared W. H. Robinson· 2 shared W. Volkmuth· 2 shared A. R. Horswill· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. M. Hummel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aging-associated augmentation of gut microbiome virulence capability drives sepsis severity.

J. F. Colbert, J. M. Kirsch, C. L. Erzen, C. J. Langouët-Astrie, G. E. Thompson, S. A. McMurtry, J. M. Kofonow, C. Robertson, E. J. Kovacs, R. C. Sullivan, J. A. Hippensteel, N. V. Sawant, N. J. De Nisco, B. D. McCollister, R. S. Schwartz, , E. P. Schmidt

This study shows that aging increases gut microbial virulence, contributing to more severe sepsis in older adults.

bioRxiv · Jan 10, 2023Microbiology

Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3

M. Casal Moura, G. E. Thompson, D. A. Nelson, L. A. Fussner, A. M. Hummel, D. E. Jenne, D. Emerling, W. Volkmuth, F. C. Fervenza, C. G. M. Kallenberg, C. A. Langford, J. W. McCune, P. A. Merkel, P. A. Monach, P. Seo, , U. Specks

The paper investigates how mutations in PR3 affect PR3-ANCA binding, finding increased binding to a variant with specific mutations.

bioRxiv · Oct 25, 2022Immunology

Remote Activation of a Latent Epitope in an Autoantigen Decoded with Simulated B-Factors

Y.-P. Pang, M. Casal Moura, G. E. Thompson, D. R. Nelson, A. M. Hummel, D. E. Jenne, D. Emerling, W. Volkmuth, W. H. Robinson, U. Specks

The paper shows that remote mutations in PR3 can activate a latent epitope, enabling antibody binding, and suggests using B-factor analysis to design therapeutics targeting autoantigens.

bioRxiv · Aug 10, 2019Biophysics