Author

W. H. Robinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. M. Hummel· 2 shared D. E. Jenne· 2 shared D. Emerling· 2 shared G. E. Thompson· 2 shared L. W. Moreland· 2 shared M. Casal Moura· 2 shared P. K. Gregersen· 2 shared U. Specks· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. M. Hummel

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Anti-citrullinated protein antibodies with diverse specificities ameliorate collagen antibody-induced arthritis in a time-dependent manner

A. M. Gomez, R. C. Brewer, J.-S. Moon, S. Acharya, S. Kongpachith, Q. Wang, S. Jahanbani, H. H. Wong, T. V. Lanz, Z. Z. Love, G. Min-Oo, A. Niedziela-Majka, W. H. Robinson

The study functionally characterizes ACPAs from RA patients and shows they reduce arthritis severity in a mouse model, with effects dependent on timing of treatment.

bioRxiv · Mar 8, 2023 · PreprintImmunology

Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3

M. Casal Moura, G. E. Thompson, D. A. Nelson, L. A. Fussner, A. M. Hummel, D. E. Jenne, D. Emerling, W. Volkmuth, F. C. Fervenza, C. G. M. Kallenberg, C. A. Langford, J. W. McCune, P. A. Merkel, P. A. Monach, P. Seo, , U. Specks

The paper investigates how mutations in PR3 affect PR3-ANCA binding, finding increased binding to a variant with specific mutations.

bioRxiv · Oct 25, 2022Immunology

Dual IgA/IgG family autoantibodies from individuals at-risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum

M. Chriswell, A. R. Lefferts, M. Clay, A. Hsu, J. Seifert, M. L. Feser, M. Maerz, C. Rims, M. Bloom, E. A. Bemis, M. K. Demoruelle, K. D. Deane, E. A. James, J. H. Buckner, W. H. Robinson, , K. A. Kuhn

Subdoligranulum spp. targeted by RA-relevant autoantibodies activate T cells in RA patients and induce autoantibodies and joint swelling in mice.

bioRxiv · Jun 9, 2022 · PreprintImmunology

Remote Activation of a Latent Epitope in an Autoantigen Decoded with Simulated B-Factors

Y.-P. Pang, M. Casal Moura, G. E. Thompson, D. R. Nelson, A. M. Hummel, D. E. Jenne, D. Emerling, W. Volkmuth, W. H. Robinson, U. Specks

The paper shows that remote mutations in PR3 can activate a latent epitope, enabling antibody binding, and suggests using B-factor analysis to design therapeutics targeting autoantigens.

bioRxiv · Aug 10, 2019Biophysics

A Systems Immunology Approach Identifies Cytokine-Induced STAT Signaling Pathways Critical to Rheumatoid Arthritis Disease Activity and Treatment Response

S. L. Bridges, J. Ptacek, R. E. Hawtin, D. Sun, B. Louie, E. Evensen, B. Mittleman, A. Cesano, G. Cavet, C. O. Bingham, S. S. Cofield, J. R. Curtis, M. I. Danila, C. Raman, R. Furie, , P. K. Gregersen

bioRxiv · Jul 8, 2019 · PreprintImmunology

High dimensional analyses of cells dissociated from cryopreserved synovial tissue

L. T. Donlin, D. A. Rao, K. Wei, K. Slowikowski, M. J. McGeachy, J. D. Turner, N. Meednu, F. Mizoguchi, M. Gutierrez-Arcelus, D. J. Lieb, J. Keegan, K. Muskat, J. Hillman, C. Rozo, E. Ricker, , M. B Brenner

This paper establishes a protocol for dissociating cryopreserved synovial tissue to obtain viable cells with preserved transcriptomes and surface markers, enabling high-dimensional analysis of rheumatoid arthritis pathology.

bioRxiv · Mar 19, 2018Immunology