Author

G. Frache

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:metabolomics· 2 Organism:mouse· 2 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. M. Decker· 1 shared B. J. Cooze· 1 shared B. R. Stockwell· 1 shared D. El Assad· 1 shared E. Moskovets· 1 shared E. Yutuc· 1 shared F. A. Yusuf· 1 shared F. Zandkarimi· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. M. Decker

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Author profile →

3 papers

Recent·Most cited

Multimodal mass spectrometry imaging reveals single-cell metabolic states in mammalian liver

H. Tian, P. R. Rajbhandari, J. Tarolli, A. M. Decker, T. V. Neelakantan, T. Angerer, F. Zandkarimi, J. Daniels, H. R. Remotti, G. Frache, N. Winograd, B. R. Stockwell

This paper develops a multimodal mass spectrometry imaging workflow to classify liver cell types and metabolic zones at single-cell resolution in human tissue.

bioRxiv · Sep 26, 2022 · PreprintCell Biology

Evaluation of 6 MALDI-Matrices for 10 μm lipid imaging and on-tissue MSn with AP-MALDI-Orbitrap

T. B. Angerer, J. Bour, J.-L. Biagi, E. Moskovets, G. Frache

This paper evaluates six MALDI matrices for lipid imaging and on-tissue MSn using AP-MALDI-Orbitrap, finding that THAP and DAN offer the best lipid coverage and signal intensity.

bioRxiv · Oct 27, 2021Biochemistry

Visualising Cholesterol in Brain by On-Tissue Derivatisation and Quantitative Mass Spectrometry Imaging

R. Angelini, E. Yutuc, M. F. Wyatt, J. Newton, F. A. Yusuf, L. Griffiths, B. J. Cooze, D. El Assad, G. Frache, W. Rao, L. B. Allen, Z. Korade, T. T. Nguyen, R. A. Rathnayake, S. M. Cologna, , W. J. Griffiths

This study uses mass spectrometry imaging to visualize cholesterol distribution in mouse brain tissue, showing reduced cholesterol in specific regions of NPC1 disease models and during development.

bioRxiv · Nov 6, 2020 · PreprintBiochemistry