G. Fusco

A heuristic model of the effects of phenotypic robustness in adaptive evolution

The paper tests a deterministic model of phenotypic robustness in adaptive evolution using a heuristic simulation, finding agreement with theoretical predictions and identifying a potential trade-off between robustness and adaptation speed.

Extent of N-terminus exposure by altered long-range interactions of monomeric alpha-synuclein determines its aggregation propensity

This study investigates how calcium-induced conformational changes in monomeric alpha-synuclein affect N-terminus exposure and aggregation propensity, identifying sequence-specific conformational differences as key factors.

Effects of phenotypic robustness on adaptive evolutionary dynamics

This study shows that phenotypic robustness is necessary for short-term adaptation and a threshold condition for long-term adaptation in evolutionary dynamics.