Author

N. Seetaloo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:protein folding & dynamics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

A. Chiki· 1 shared A. D. Stephens· 1 shared A. De Simone· 1 shared C. Aicart-Ramos· 1 shared F. Balaguer-Perez· 1 shared F. D. Sobott· 1 shared F. Moreno-Herrero· 1 shared F. Sobott· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Chiki

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DNA binding and bridging by human CtIP in the healthy and diseased states

S. Lokanathan Balaji, S. De Braganca, F. Balaguer-Perez, S. Northall, O. J. Wilkinson, C. Aicart-Ramos, F. Sobott, N. Seetaloo, F. Moreno-Herrero, M. S. Dillingham

This study investigates the DNA binding and bridging activities of CtIP in healthy and diseased states, identifying a C-terminal DNA-binding domain and showing that tetramerization is required for DNA bridging.

bioRxiv · Dec 14, 2023 · PreprintBiochemistry

HDfleX: Software for flexible high structural resolution of hydrogen/deuterium-exchange mass spectrometry data

N. Seetaloo, M. Kish, J. J. Phillips

HDfleX enables the integration and analysis of HDX-MS data at multiple structural resolutions, including intact protein, peptide, and fragment levels.

bioRxiv · Dec 9, 2021Biophysics

Extent of N-terminus exposure by altered long-range interactions of monomeric alpha-synuclein determines its aggregation propensity

A. D. Stephens, M. Zacharopoulou, R. Moons, G. Fusco, N. Seetaloo, A. Chiki, P. J. Hooper, I. Mela, H. A. Lashuel, J. J. Philips, A. De Simone, F. D. Sobott, G. S. Kaminski Schierle

This study investigates how calcium-induced conformational changes in monomeric alpha-synuclein affect N-terminus exposure and aggregation propensity, identifying sequence-specific conformational differences as key factors.

bioRxiv · Aug 20, 2019 · PreprintBiophysics