Author

G. Holt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Griswold· 1 shared A. Ojewole· 1 shared A. U. Lowegard· 1 shared A. V. Schally· 1 shared B. Donald· 1 shared C. Zhang· 1 shared E. M. Dreifus· 1 shared J. Jou· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. J. Griswold

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2 papers

Recent·Most cited

Activity of the GHRH Antagonist MIA602 and its Underlying Mechanisms of Action in sarcoidosis

C. Zhang, R. Tian, E. M. Dreifus, G. Holt, R. Cai, A. J. Griswold, P. Bejarano, R. Jackson, A. V. Schally, M. Mirsaeidi

This study investigates the anti-inflammatory effects of MIA602, a GHRH antagonist, in sarcoidosis by analyzing its impact on cytokine levels and cellular markers in vitro and in vivo.

bioRxiv · Aug 19, 2020 · PreprintImmunology

Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD:KRas protein-protein interface

A. U. Lowegard, M. Frenkel, J. Jou, A. Ojewole, G. Holt, B. Donald

This paper introduces two provable algorithms for efficient computational protein design and applies them to redesign the c-Raf-RBD:KRas interface, achieving high accuracy in predicting and validating mutations.

bioRxiv · Oct 2, 2019Biochemistry