Author

J. Jou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

A. K. Rustgi· 1 shared A. Ojewole· 1 shared A. Thomas-Tikhonenko· 1 shared A. U. Lowegard· 1 shared B. Donald· 1 shared B. W. Katona· 1 shared B. Z. Stanger· 1 shared C. B. Aarons· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. K. Rustgi

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Author profile →

2 papers

Recent·Most cited

Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment

N. Li, Q. Zhu, Y. Tian, K. J. Ahn, X. Wang, Z. Cramer, I. W. Folkert, P. Yu, J. Jou, S. Adams-Tzivelekidis, P. Sehgal, N. N. Mahmoud, C. B. Aarons, R. E. Roses, A. Thomas-Tikhonenko, , C. J. Lengner

This study maps and models human colorectal carcinoma interactions with the tumor microenvironment using single-cell transcriptomics and tumoroid cultures, showing how tumoroids suppress inflammation and reprogram macrophages.

bioRxiv · Sep 13, 2022Cancer Biology

Novel, provable algorithms for efficient ensemble-based computational protein design and their application to the redesign of the c-Raf-RBD:KRas protein-protein interface

A. U. Lowegard, M. Frenkel, J. Jou, A. Ojewole, G. Holt, B. Donald

This paper introduces two provable algorithms for efficient computational protein design and applies them to redesign the c-Raf-RBD:KRas interface, achieving high accuracy in predicting and validating mutations.

bioRxiv · Oct 2, 2019Biochemistry