Involvement of the splicing factor SART1 in the BRCA1-dependent homologous recombination repair of DNA double-strand breaks
M. Yamauchi, R. Kato, T. Yasuhara, Y. Uchihara, M. Hirakawa, K. Ozaki, Y. Abe, H. Shibata, R. Kawabata-Iwakawa, A. Shakayeva, P. Kot, K. Miyagawa, K. Suzuki, A. Shibata, N. Matsuda
This study shows SART1 promotes DSB end resection in HR, cooperates with BRCA1 to counteract 53BP1/RIF1, and is required for BRCA1 recruitment to DSBs.
bioRxiv · Sep 7, 2023 · PreprintCell Biology