Author

G. L. Hamilton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. Sanabria· 3 shared F. Ding· 2 shared N. Saikia· 2 shared A. Barth· 1 shared C. A. M. Seidel· 1 shared C. A. Seidel· 1 shared C. de Lannoy· 1 shared C. Gebhardt· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

H. Sanabria

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Author profile →

3 papers

Recent·Most cited

Fuzzy Supertertiary Interactions within PSD-95 Enable Ligand Binding

M. E. Bowen, H. Sanabria, F. Ding, C. A. Seidel, Y. Hao, C. Zhang, j. Kubiak, F. Wu, F. S. Welcome, S. Basak, N. Saikia, G. L. Hamilton

This study uses molecular dynamics and FRET to analyze PSD-95's conformational dynamics and shows how its flexible structure enables ligand binding.

bioRxiv · Feb 23, 2022Biophysics

Inferring kinetic rate constants from single-molecule FRET trajectories - a blind benchmark of kinetic analysis tools

M. Götz, A. Barth, S. S.- R. Bohr, R. Börner, J. Chen, T. Cordes, D. A. Erie, C. Gebhardt, M. C. A. S. Hadzic, G. L. Hamilton, N. S. Hatzakis, T. Hugel, L. Kisley, D. C. Lamb, C. de Lannoy, , S. Schmid

This study benchmarks eleven tools for inferring kinetic rate constants from smFRET trajectories using simulated and experimental data with varying challenges.

bioRxiv · Nov 23, 2021Biophysics

Ensemble Switching Unveils a Kinetic Rheostat Mechanism of the Eukaryotic Thiamine PyrophosphateRiboswitch

J. Ma, N. Saikia, S. Godar, G. L. Hamilton, F. Ding, J. Alper, H. Sanabria

This study reveals a kinetic rheostat mechanism in the Arabidopsis thiamine pyrophosphate riboswitch through ensemble switching dynamics involving TPP and Mg2+ interactions.

bioRxiv · Mar 12, 2021Biophysics