Author

G. Le Lay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

M. Bernard· 2 shared P. Vargas· 2 shared A. Fischer· 1 shared A. Krueger· 1 shared A. Meneses· 1 shared A. Palladini· 1 shared A. Sinha· 1 shared B. Neven· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

M. Bernard

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Actin dynamics regulation by TTC7A/PI4KIIIα axis limits DNA damage and cell death during leukocyte migration

T. Gajardo, M. Lo, M. Bernard, C. Leveau, M.-T. El-Daher, M. Kurowska, G. Le Lay, D. Moshous, B. Neven, A. Fischer, G. Menasche, G. de Saint Basile, P. Vargas, F. E. Sepulveda

This study shows TTC7A deficiency impairs leukocyte migration, leading to DNA damage and cell death during chemotaxis in dense environments.

bioRxiv · Oct 14, 2021 · PreprintImmunology

HIF2α is a Direct Regulator of Neutrophil Motility

S. Sormendi, M. Deygas, A. Sinha, A. Krueger, I. Kourtzelis, G. Le Lay, M. Bernard, P. Saez, M. Gerlach, K. Franke, A. Meneses, M. Kraeter, A. Palladini, J. Guck, U. Coskun, , B. Wielockx

This study identifies HIF2α as a regulator of neutrophil motility through the PHD2-HIF2-RhoA axis, enhancing migration in hypoxic environments during inflammation.

bioRxiv · Jun 5, 2020Immunology