Author

K. Franke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

A. de jong· 1 shared A. Krueger· 1 shared A. Meneses· 1 shared A. Palladini· 1 shared A. Sinha· 1 shared B. van Steensel· 1 shared B. Wielockx· 1 shared C. J. Binder· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. de jong

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Author profile →

3 papers

Recent·Most cited

HIF2α is a Direct Regulator of Neutrophil Motility

S. Sormendi, M. Deygas, A. Sinha, A. Krueger, I. Kourtzelis, G. Le Lay, M. Bernard, P. Saez, M. Gerlach, K. Franke, A. Meneses, M. Kraeter, A. Palladini, J. Guck, U. Coskun, , B. Wielockx

This study identifies HIF2α as a regulator of neutrophil motility through the PHD2-HIF2-RhoA axis, enhancing migration in hypoxic environments during inflammation.

bioRxiv · Jun 5, 2020Immunology

SIRPalpha on mouse B1 cells restricts lymphoid tissue migration and natural antibody production

T. van den Berg, K. Franke, S. Y. Pillai, M. Hoogenboezem, M. J. J. Gijbels, H. L. Matlung, J. Geissler, H. Olsman, C. Pottgens, P. J. van Gorp, M. Ozsvar-Kozma, Y. Saito, T. Matozaki, T. W. Kuijpers, R. W. Hendriks, , M. P. J. de Winther

This study shows SIRPalpha on mouse B1 cells limits migration and natural antibody production, suggesting it as a therapeutic target for atherosclerosis.

bioRxiv · May 13, 2020Immunology

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner

M. Balzarolo, S. Engels, A. de jong, K. Franke, T. K. van den Berg, E. M. Janssen, B. van Steensel, M. Wolkers

This study shows that m6A methylation on specific DNA sequences enhances immune recognition by macrophages and dendritic cells through STING-dependent pathways, with sequence-specific immunostimulatory or suppressive effects.

bioRxiv · Aug 21, 2019Immunology