G. Lim

14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation

This study shows 14-3-3ζ regulates adipogenesis by modulating chromatin accessibility in adipose precursor cells, impacting gene expression and fat mass.

Crossover Interference Mediates Multiscale Patterning Along Meiotic Chromosomes

The paper reveals a two-tiered crossover patterning mechanism in budding yeast meiosis, with mechanical forces and Pch2/TRIP13 modulating triad components.

14-3-3ζ mediates an alternative, non- thermogenic mechanism to reduce heat loss and improve cold tolerance

This paper shows that overexpressing 14-3-3ζ in mice improves cold tolerance by reducing heat loss through increased vasoconstriction, independent of thermogenesis.

Reducing 14-3-314-3-3ζ expression influences adipocyte maturity and impairs function

This study shows that reducing 14-3-3ζ expression impairs adipocyte maturity and lipolysis in mice and 3T3-L1 cells by affecting lipidomic profiles and gene expression.

Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA splicing factors during adipogenesis

The paper identifies novel adipogenic factors and RNA splicing regulators in the 14-3-3ζ interactome, showing their roles in adipocyte differentiation and alternative splicing.