Author

C. Des Rosiers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

I. Robillard Frayne· 2 shared M. Ruiz· 2 shared A. Oppong· 1 shared A. Vivoli· 1 shared A. Yamashita· 1 shared A.-L. Castell· 1 shared B. Bouchard· 1 shared C. Bouzin· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

I. Robillard Frayne

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A NRF2/beta3-adrenoreceptor axis drives a sustained antioxidant and metabolic rewiring through the pentose-phosphate pathway to alleviate cardiac stress

L. Michel, H. Esfahani, R. Verdoy, D. de Mulder, J. Ambroise, V. Roelants, B. Bouchard, J. Savary, J. Dewulf, T. Doumont, C. Bouzin, V. Haufroid, J. J. F. P. Luiken, M. Nabben, M. Singleton, , J.-L. Balligand

This study identifies a NRF2/beta3-adrenoreceptor axis that enhances antioxidant defenses and metabolic rewiring via the pentose-phosphate pathway, protecting cardiac function under stress.

bioRxiv · Nov 10, 2023Physiology

Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.

A. Yamashita, O. Ignatenko, M. Nguyen, R. Lambert, K. Watt, C. Daneault, I. Robillard-Frayne, I. Topisirovic, C. Des Rosiers, H. M. McBride

The paper investigates the effects of LONP2 depletion on peroxisomal function and cholesterol metabolism, revealing cell-type-specific responses and implications for peroxisomal disorders.

bioRxiv · Mar 15, 2023Cell Biology

Very Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation

A.-L. Castell, A. Vivoli, T. S. Tippetts, I. Robillard Frayne, V. S. Moulle, M. Ruiz, J. Ghislain, C. Des Rosiers, W. L. Holland, S. A. Summers, V. Poitout

This study shows that oleate induces β-cell proliferation in rats via unsaturated very long-chain sphingolipids, mediated by ACBP and ELOVL1.

bioRxiv · Jul 16, 2021Cell Biology

Reducing 14-3-314-3-3ζ expression influences adipocyte maturity and impairs function

A. Oppong, K. Diallo, I. Robillard Frayne, C. Des Rosiers, G. Lim

This study shows that reducing 14-3-3ζ expression impairs adipocyte maturity and lipolysis in mice and 3T3-L1 cells by affecting lipidomic profiles and gene expression.

bioRxiv · Feb 24, 2020Physiology