Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells
E. Rivers, R. Rai, J. Lotscher, M. Hollinshead, G. Markelj, J. Thaventheran, A. Worth, A. Cavazza, C. Hess, M. Bajaj-Elliott, A. J. Thrasher
This study shows that WASp deficiency impairs autophagy and mitochondrial function in human myeloid cells, with ARP2/3 dependency and metabolic consequences.
bioRxiv · Feb 6, 2020Physiology