Proteogenomic Characterization Reveals Therapeutic Opportunities Related to Mitochondrial Function in Melanoma
J. Gil, Y. Kim, V. Doma, U. Cakır, M. Kuras, L. Betancourt, I. Pla Parada, A. Sanchez, Y. Sugihara, R. Appelqvist, H. Oskolas, B. Lee, J. de Siqueira Guedes, G. Monnerat, G. Reis Alves Carneiro, , G. Marko-Varga
This study uses proteomics to analyze mitochondrial function in melanoma samples, finding dysregulation linked to patient survival and treatment responses, and proposes therapeutic strategies targeting mitochondrial pathways.
bioRxiv · Oct 24, 2022 · PreprintCancer Biology