Author

D. Fenyö

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Cell Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 7 Approach:experimental assay· 5 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

A. M. Szasz· 2 shared A. Sanchez· 2 shared B. Baldetorp· 2 shared B. Lee· 2 shared E. Wieslander· 2 shared G. B. Domont· 2 shared G. Marko-Varga· 2 shared G. Monnerat· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. M. Szasz

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Proteogenomic Characterization Reveals Therapeutic Opportunities Related to Mitochondrial Function in Melanoma

J. Gil, Y. Kim, V. Doma, U. Cakır, M. Kuras, L. Betancourt, I. Pla Parada, A. Sanchez, Y. Sugihara, R. Appelqvist, H. Oskolas, B. Lee, J. de Siqueira Guedes, G. Monnerat, G. Reis Alves Carneiro, , G. Marko-Varga

This study uses proteomics to analyze mitochondrial function in melanoma samples, finding dysregulation linked to patient survival and treatment responses, and proposes therapeutic strategies targeting mitochondrial pathways.

bioRxiv · Oct 24, 2022 · PreprintCancer Biology

PTK7 is a positive allosteric modulator of GPR133 (ADGRD1) signaling in GBM

J. D. Frenster, H. Erdjument-Bromage, W. Liu, G. Stephan, N. Ravn-Boess, D. Bready, J. Wilcox, B. Kieslich, M. Jankovic, C. Wilde, S. Horn, N. Straeter, I. Liebscher, T. Schoneberg, D. Fenyö, , D. G. Placantonakis

This study identifies PTK7 as a positive allosteric modulator of GPR133 signaling in glioblastoma, showing that their interaction enhances receptor activation and is relevant to tumor pathogenesis.

bioRxiv · Jun 15, 2022 · PreprintCell Biology

Proteogenomics Reveals how Metastatic Melanoma Modulates the Immune System to Allow Immune Evasion

J. Gil, Y. Kim, B. Szeitz, V. Doma, U. Cakır, N. Pinto de Almeida, Y. Paco Hagemeijer, V. Guryev, J. G. Johansson, Y. Sharma, I. Pla Parada, Z. Horvath, J. de Siqueira Guedes, G. Monnerat, F. C. Nogueira, , G. Marko-Varga

This paper analyzes proteogenomic data from melanoma patients to show how metastatic melanoma alters metabolism and immune responses to evade immune detection.

bioRxiv · Apr 10, 2021 · PreprintCancer Biology

Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2

F. D. Mast, P. C. Fridy, N. E. Ketaren, J. Wang, E. Y. Jacobs, J. P. Olivier, T. Sanyal, K. R. Molloy, F. Schmidt, M. Rutkowska, Y. Weisblum, L. M. Rich, E. R. Vanderwall, N. Dambrauskas, V. Vigdorovich, , M. P. Rout

This paper presents a large repertoire of high-affinity nanobodies against SARS-CoV-2 Spike protein with potent neutralization properties and resistance to viral variants.

bioRxiv · Apr 8, 2021Biochemistry

LINE-1 ORF1p RIP-seq reveals widespread association with p-body enriched mRNAs

E. M. Briggs, W. McKerrow, P. Mita, J. D. Boeke, S. K. Logan, D. Fenyö

The paper uses RIP-seq and L1EM analysis to show ORF1p binds non-LINE-1 mRNAs and p-body enriched RNAs in prostate cancer cells, correlating with LINE-1 RNA levels in TCGA tumors.

bioRxiv · Aug 20, 2020Cell Biology

LINE-1 expression in cancer correlates with DNA damage response, copy number variation, and cell cycle progression

W. McKerrow, X. Wang, P. Mita, S. Cao, M. Grivainis, L. Ding, J. LaCava, J. Boeke, D. Fenyö

bioRxiv · Jun 26, 2020 · PreprintCancer Biology

The ULK1-FBXW5-SEC23B nexus controls autophagy

M. Pagano, Y.-T. Jeong, D. Simoneschi, S. Keegan, D. Melville, N. Adler, A. Saraf, L. Florens, M. P. Washburn, C. Cavasotto, D. Fenyö, A. M. Cuervo, M. Rossi

This study identifies the ULK1-FBXW5-SEC23B pathway as a regulator of autophagy by controlling COPII localization and SEC23B stability during nutrient starvation.

bioRxiv · Oct 12, 2018Cell Biology