Author

G. N. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Plant Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. A. Herrmann· 2 shared J.-M. Schwartz· 2 shared K. J. Kowalski· 2 shared N. Wagle· 2 shared P. I. Calzadilla· 2 shared P. Mao· 2 shared A. G. Waks· 1 shared A. Letai· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPlant Biology

H. A. Herrmann

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Author profile →

5 papers

Recent·Most cited

Genetically-based adaptive trait shifts at an expanding mangrove range margin

J. P. Kennedy, G. N. Johnson, R. F. Preziosi, J. K. Rowntree

This study confirms a genetic basis for adaptive trait shifts in mangroves expanding to cooler range margins, showing improved survival and growth under harsh conditions.

Hydrobiologia · Mar 8, 2022Peer-reviewedEcology

Cytosolic fumarase acts as a metabolic fail-safe for both high and low temperature acclimation of Arabidopsis thaliana

H. A. Herrmann, P. I. Calzadilla, J.-M. Schwartz, G. N. Johnson

This study identifies cytosolic fumarase FUM2 as a metabolic fail-safe in Arabidopsis thaliana, maintaining system stability during both high and low temperature acclimation.

bioRxiv · Apr 19, 2021Plant Biology

Cell line-specific network models of ER+ breast cancer identify PI3Kα inhibitor sensitivity factors and drug combinations

J. Gomez Tejeda Zanudo, P. Mao, C. Alcon, K. J. Kowalski, G. N. Johnson, G. Xu, J. Baselga, M. Scaltriti, A. Letai, J. Montero, R. Albert, N. Wagle

bioRxiv · Aug 25, 2020Cancer Biology

A Failure Mode and Effect Analysis of plant metabolism reveals why cytosolic fumarase is required for temperature acclimation in Arabidopsis

H. A. Herrmann, P. I. Calzadilla, J.-M. Schwartz, G. N. Johnson

This study uses FMEA to show that fumarate, catalyzed by FUM2, is critical for temperature acclimation in Arabidopsis by maintaining metabolic stability.

bioRxiv · Aug 4, 2020 · PreprintPlant Biology

The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors in patients with hormone receptor positive metastatic breast cancer

S. A. Wander, O. Cohen, X. Gong, G. N. Johnson, J. Buendia-Buendia, M. R. Lloyd, D. Kim, F. Luo, P. Mao, K. Helvie, K. J. Kowalski, U. Nayar, A. G. Waks, S. Parsons, R. Martinez, , N. Wagle

The paper identifies eight resistance mechanisms to CDK4/6 inhibitors in HR+ breast cancer, present in 80% of resistant tumors, with potential therapeutic strategies.

bioRxiv · Nov 28, 2019Cancer Biology