Author

G. Negro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Abdollahi· 1 shared A. Dubrovska· 1 shared A. Franken· 1 shared A. Linge· 1 shared A. Mukha· 1 shared A. Suma· 1 shared B. Aschenbrenner· 1 shared B. Behrens· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Abdollahi

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2 papers

Recent·Most cited

Cluster size determines internal structure of transcription factories in human cells

M. Semeraro, G. Negro, G. Forte, A. Suma, G. Gonnella, P. R. Cook, D. Marenduzzo

This study develops a chromatin polymer model to show that cluster size determines whether transcription factories are specialised or mixed, reconciling conflicting experimental results.

bioRxiv · Jan 16, 2023Biophysics

GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy

A. Mukha, U. Kahya, A. Linge, O. Chen, S. Lock, V. Lukiyanchuk, S. Richter, T. C. Alves, M. Peitzsch, V. Telychko, S. Skvortsov, G. Negro, B. Aschenbrenner, I.-I. Skvortsova, P. Mirtschink, , A. Dubrovska

This study shows that glutamine catabolism via GLS regulates redox state, stemness, and autophagy in prostate cancer, affecting radiosensitivity and patient outcomes.

bioRxiv · Jan 7, 2021Cancer Biology