Author

N. J. Darling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:trajectory inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

P. Cohen· 2 shared T. Segura· 2 shared A. R. Anderson· 1 shared A. Schuettelkopf· 1 shared C. Mackay· 1 shared C. Pong· 1 shared C. S. Hill· 1 shared D. R. Squair· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

P. Cohen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SDF-1 Bound Heparin Nanoparticles Recruit Progenitor Cells for Their Differentiation and Promotion of Angiogenesis After Stroke

T. Segura, K. L. Wilson, L. A. Onweller, N. I. Joseph, J. David-Bercholz, N. J. Darling

This study develops heparin-norbornene nanoparticles with SDF-1 to recruit progenitor cells and promote angiogenesis after stroke, achieving revascularization in 10 days.

bioRxiv · Jul 5, 2023Bioengineering

Salt-inducible kinase (SIK) inhibition is protective in a mouse model of asthma

M. van Gijsel-Bonnello, N. J. Darling, L. McDonald, M. Sime, J. Clark, M. Mezna, A. Schuettelkopf, C. Mackay, J. Bower, H. McKinnon, P. Cohen, S. Arthur

This study shows that inhibiting SIKs reduces IL-13 secretion from ILC2s and alleviates allergic asthma symptoms in mice.

bioRxiv · Jun 7, 2021 · PreprintImmunology

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses

L. D. Hutchinson, N. J. Darling, S. Nicolaou, I. Gori, D. R. Squair, P. Cohen, C. S. Hill, G. P. Sapkota

The paper identifies salt-inducible kinases (SIKs) as regulators of TGFβ-mediated transcriptional and apoptotic responses through pharmacological and genetic approaches.

bioRxiv · Oct 17, 2019Cancer Biology

Click by Click Microporous Annealed Particle (MAP) Scaffolds

N. J. Darling, W. Xi, E. Sideris, A. R. Anderson, C. Pong, S. T. Carmichael, T. Segura

This paper develops a tunable MAP scaffold using click chemistry to adjust hydrogel rigidity and demonstrates its biocompatibility in an ischemic stroke model.

bioRxiv · Sep 12, 2019Bioengineering