Author

K. Dunbar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. P. Sapkota· 2 shared T. Macartney· 2 shared A. Lima· 1 shared A. Valanciute· 1 shared A.-M. Ochocka-Fox· 1 shared F. V. N. Din· 1 shared J. Blackmur· 1 shared J. C. Smith· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

G. P. Sapkota

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IMiDs induce FAM83F degradation via an interaction with CK1α to attenuate Wnt signalling

G. P. Sapkota, K. Dunbar, T. Macartney

This study shows IMiDs degrade FAM83F via CK1α interaction, reducing Wnt signaling in colorectal cancer cells.

bioRxiv · May 25, 2020Cancer Biology

FAM83F regulates canonical Wnt signalling through an interaction with CK1α

K. Dunbar, R. A. Jones, K. S. Dingwell, T. Macartney, J. C. Smith, G. P. Sapkota

This study identifies FAM83F as a regulator of canonical Wnt signaling through its interaction with CK1α, showing it enhances signaling in Xenopus embryos and human colorectal cancer cells.

bioRxiv · May 25, 2020Cell Biology

Aspirin-mediated DKK-1 increase rescues Wnt-driven stem-like phenotype in human intestinal organoids

K. Dunbar, A. Valanciute, V. Rajasekaran, T. Jamieson, P. Freile Vinuela, A. Lima, J. Blackmur, A.-M. Ochocka-Fox, M. J. Arends, O. J. Sansom, K. B. Myant, S. M. Farrington, M. G. Dunlop, F. V. N. Din

The paper shows aspirin reduces Wnt-driven stem-like traits in intestinal organoids by increasing DKK-1, suggesting a mechanism for its anti-cancer effects.

bioRxiv · Oct 17, 2019 · PreprintCancer Biology