G. Palacios

An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion.

The paper shows that early arginine methylation of KCa3.1 limits Ca2+-mediated NFAT1 activation, preventing T cell exhaustion during activation.

Mitochondrial proteostasis mediated by CRL5Ozz and Alix maintains skeletal muscle function

This study identifies CRL5Ozz and Alix as regulators of mitochondrial proteostasis by controlling Slc25A4 levels, which impacts mitochondrial function and muscle fiber composition.

Integrated multivariate analysis of transcriptomic data reveals immunological mechanisms in mice after Leishmania infantum infection

The paper uses multivariate analysis of transcriptomic data to identify immunological changes in mice infected with Leishmania infantum.

Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis)

This study uses CT and PET/CT imaging to quantify SARS-CoV-2-induced lung abnormalities in crab-eating macaques, providing an objective endpoint for evaluating medical countermeasures.

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry

The paper shows that tibrovirus glycoproteins can enter human, bat, and nonhuman primate cells, but replication resistance varies among cell types.