Author

G. S. Taylor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

M. Pugh· 2 shared A. Angelillo-Scherrer· 1 shared A. Culhane· 1 shared A. Gazdhar· 1 shared A. Tardivel· 1 shared B. E. Willcox· 1 shared B. Hargitai· 1 shared B. Willcox· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

M. Pugh

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Author profile →

3 papers

Recent·Most cited

Multi-omic spatial profiling reveals the unique virus-driven immune landscape of COVID-19 placentitis

M. Pugh, E. Fennel, C. I. Leahy, T. Perry, B. Hargitai, T. Marton, K. J. Hunter, G. Halford, H. O. Yilmaz, Z. Stamataki, G. Reynolds, H. J. Hill, B. E. Willcox, N. M. Steven, C. A. Thornton, , G. S. Taylor

The paper uses multi-omic spatial profiling to show that SARS-CoV-2 infection in the placenta leads to a distinct immune signature with PDL1-expressing macrophages and T-cell exclusion.

bioRxiv · Nov 14, 2022 · PreprintImmunology

LRR protein RNH1 dampens the inflammasome activation and is associated with adverse clinical outcomes in COVID-19 patients

G. Bombaci, M. A. Sarangdhar, N. Andina, A. Tardivel, E. C.-W. Yu, G. M. Mackie, M. Pugh, V. B. Ozan, Y. Banz, T. Spinetti, C. Hirzel, E. Youd, J. C. Schefold, G. S. Taylor, A. Gazdhar, , R. Allam

This study identifies RNH1 as an inhibitor of inflammasome activation, showing its protective role in limiting inflammation and its association with worse outcomes in COVID-19.

bioRxiv · Apr 12, 2021 · PreprintImmunology

Age related defects in NK cell immunity revealed by deep immune profiling of pediatric cancer patients

E. Syrimi, N. Khan, P. Murray, C. Willcox, T. Haigh, B. Willcox, N. Masand, J. Zuo, S. Barone, J. Irish, P. Kearns, G. S. Taylor

The paper uses high dimensional single cell analysis to reveal age-related immune changes in NK and T-cells of pediatric cancer patients and age-matched healthy children.

bioRxiv · Mar 9, 2020 · PreprintImmunology