Author

G. Reynolds

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Ecology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Research Focus:ecology & biodiversity· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

M. Haniffa· 3 shared A. Filby· 2 shared A. Hector· 2 shared D. Dixon· 2 shared D. F. R. P. Burslem· 2 shared D. Maunder· 2 shared D.-M. Popescu· 2 shared E. Stephenson· 2 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

M. Haniffa

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Logging alters tropical forest structure, while conversion to agriculture reduces biodiversity and functioning

C. J. Marsh, E. C. Turner, B. W. Blonder, B. Bongalov, S. Both, R. S. Cruz, D. M. O. Elias, D. Hemprich-Bennett, P. Jotan, V. Kemp, U. H. Kritzler, S. Milne, D. T. Milodowski, S. L. Mitchell, M. Montoya Pillco, , A. Hector

The paper analyzes the impacts of logging and conversion to oil palm on tropical forest structure, biodiversity, and functioning in Borneo, finding that logging affects structure more than biodiversity, while conversion has greater impacts on biodiversity and functioning.

bioRxiv · Dec 15, 2022 · PreprintEcology

Multi-omic spatial profiling reveals the unique virus-driven immune landscape of COVID-19 placentitis

M. Pugh, E. Fennel, C. I. Leahy, T. Perry, B. Hargitai, T. Marton, K. J. Hunter, G. Halford, H. O. Yilmaz, Z. Stamataki, G. Reynolds, H. J. Hill, B. E. Willcox, N. M. Steven, C. A. Thornton, , G. S. Taylor

The paper uses multi-omic spatial profiling to show that SARS-CoV-2 infection in the placenta leads to a distinct immune signature with PDL1-expressing macrophages and T-cell exclusion.

bioRxiv · Nov 14, 2022 · PreprintImmunology

Positive effects of tree diversity on tropical forest restoration in a field-scale experiment

R. Veryard, J. Wu, M. J. O'Brien, R. Anthony, S. Both, D. F. R. P. Burslem, B. Chen, E. Fernandez-Miranda Cagigal, H. C. J. Godfray, E. Godoong, S. Liang, P. Saner, B. Schmid, Y. Sau Wai, J. Xie, , A. Hector

This study shows that planting diverse tree mixtures in logged forests accelerates restoration rates in a large field experiment.

bioRxiv · Sep 9, 2022Ecology

Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2

C. F. Hatton, R. A. Botting, M. E. Duenas, I. J. Haq, B. Verdon, B. J. Thompson, J. Stremenova Spegarova, F. Gothe, E. A. Stephenson, A. I. Gardner, S. Murphy, J. Scott, J. P. Garnett, S. Carrie, J. Powell, , C. J. A. Duncan

This study shows that delayed type I and III interferon responses in nasal epithelial cells allow SARS-CoV-2 replication, but pre-infection IFN treatment restricts virus and preserves barrier integrity.

bioRxiv · Feb 17, 2021Immunology

Poised cell circuits in human skin are activated in disease

G. Reynolds, P. Vegh, J. Fletcher, E. Poyner, E. Stephenson, I. Goh, R. Botting, N. Huang, B. Olabi, A. Dubois, D. Dixon, K. Green, D. Maunder, J. Engelbert, M. Efremova, , F. Watt

The paper creates a single-cell atlas of human skin, showing how cell circuits change in inflammatory diseases like atopic dermatitis and psoriasis.

bioRxiv · Nov 5, 2020 · PreprintImmunology

A cell atlas of human thymic development defines T cell repertoire formation

J.-E. Park, R. A. Botting, C. Dominguez Conde, D.-M. Popescu, M. Lavaert, D. J. Kunz, E. Stephenson, R. Ragazzini, E. Tuck, A. L. Wilbrey-Clark, J. R. Ferdinand, S. Webb, D. Maunder, N. Vandamme, K. T. Mahbubani, , S. A. Teichmann

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.

bioRxiv · Jan 28, 2020Immunology

Donor monocyte-derived macrophages promote human acute graft versus host disease

L. Jardine, U. Cytlak, M. Gunawan, G. Reynolds, K. Green, X.-N. Wang, S. Pagan, M. Pradnya, C. A. Lamb, A. K. Long, E. Hurst, S. Nair, G. Jackson, A. Publicover, V. Bigley, , M. Collin

The paper identifies donor monocyte-derived macrophages as key players in human acute graft versus host disease, showing their enhanced activation of T cells and secretion of inflammatory cytokines.

bioRxiv · Sep 30, 2019Immunology

The mechanical stability of the worlds tallest broadleaf trees

T. D. Jackson, A. F. Shenkin, N. Majalap, J. bin Jami, A. bin Sailim, G. Reynolds, D. Coomes, C. Chandler, D. Boyd, A. Burt, P. Wilkes, M. Disney

This study examines mechanical stability factors limiting tree height in tall tropical trees, finding that wind damage risk increases with height despite larger diameters, leading to a U-shaped mechanical risk curve.

bioRxiv · Jun 10, 2019Ecology