Author

H. J. Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

Z. Stamataki· 3 shared S. P. Davies· 2 shared A. Culhane· 1 shared A. Garai· 1 shared A. Richardson· 1 shared B. E. Willcox· 1 shared B. Hargitai· 1 shared C. A. J. Hooper· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Z. Stamataki

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multi-omic spatial profiling reveals the unique virus-driven immune landscape of COVID-19 placentitis

M. Pugh, E. Fennel, C. I. Leahy, T. Perry, B. Hargitai, T. Marton, K. J. Hunter, G. Halford, H. O. Yilmaz, Z. Stamataki, G. Reynolds, H. J. Hill, B. E. Willcox, N. M. Steven, C. A. Thornton, , G. S. Taylor

The paper uses multi-omic spatial profiling to show that SARS-CoV-2 infection in the placenta leads to a distinct immune signature with PDL1-expressing macrophages and T-cell exclusion.

bioRxiv · Nov 14, 2022 · PreprintImmunology

Supramolecular cylinders target bulge structures in the 5-prime UTR of the RNA genome of SARS-CoV-2 and inhibit viral replication

L. Melidis, H. J. Hill, N. J. Coltman, S. P. Davies, K. Winczura, T. Chauhan, J. S. Craig, A. Garai, C. A. J. Hooper, R. T. Egan, J. A. McKeating, N. J. Hodges, Z. Stamataki, P. Grzechnik, M. J. Hannon

The paper models the 5' UTR structure of SARS-CoV-2 and shows supramolecular cylinders bind to a bulge and junction, inhibiting viral replication.

bioRxiv · Mar 30, 2021Biochemistry

The hyperlipidaemic drug fenofibrate significantly reduces infection by SARS-CoV-2 in cell culture models

S. P. Davies, C. J. Mycroft-West, I. Pagani, H. J. Hill, Y.-H. Chen, R. T. Karlsson, I. Bagdonaite, S. E. Guimond, Z. Stamataki, M. A. Lima, J. E. Turnbull, Z. Yang, E. E. Vicenzi, M. A. Skidmore, F. Khanim, A. Richardson

This study shows fenofibrate and its metabolite fenofibric acid reduce SARS-CoV-2 infection in cell culture by up to 70% at clinically achievable concentrations.

bioRxiv · Jan 10, 2021Pharmacology & Toxicology