Author

G. Shibu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Akagbosu· 2 shared C. Leslie· 2 shared A. Y. Rudensky· 1 shared C. Brown· 1 shared C. C. Brown· 1 shared C. Friedrich· 1 shared D. Deep· 1 shared G. Gasteiger· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

B. Akagbosu

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Author profile →

2 papers

Recent·Most cited

Thetis cells induce food-specific Treg cell differentiation and oral tolerance

Y. Parisotto, V. Cabric, T. Park, B. Akagbosu, Z. Zhao, Y. Lo, L. Fisher, G. Shibu, Y. Paucar Iza, C. Leslie, C. Brown

This study identifies Thetis cells IV as essential for food-specific Treg cell differentiation and oral tolerance, highlighting their distinct role from dendritic cells in immune regulation.

bioRxiv · May 8, 2024 · PreprintImmunology

A novel RORγt+ antigen presenting cell type instructs microbiota-dependent regulatory T cell differentiation and tolerance during early life

B. Akagbosu, Z. Tayyebi, G. Shibu, Y. A. Paucar Iza, D. Deep, Y. Franco Parisotto, H. A. Pasolli, V. Thevin, R. Elmentaite, M. Knott, S. Hemmers, L. Jahn, C. Friedrich, J. Verter, Z. Wang, , C. C. Brown

This study identifies a new RORγt+ antigen-presenting cell type, Thetis cells, that drives microbiota-dependent regulatory T cell differentiation and tolerance during early life.

bioRxiv · Feb 26, 2022Immunology