Author

G. Thwaites

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 2 Organism:chicken / avian· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

N. H. Phu· 3 shared S. Baker· 3 shared B. T. Kiet· 2 shared C. Nguyen Ngoc Minh· 2 shared D. D. A. Thu· 2 shared H. Chung The· 2 shared J. Carrique-Mas· 2 shared L. J. Hall· 2 shared

Activity by Year

2020-2022 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersMicrobiology

N. H. Phu

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Mucosal microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients

H. N. H. Tran, T. Nguyen Hoang Thu, P. H. Nguyen, C. N. Vo, K. V. Doan, C. Nguyen Ngoc Minh, N. T. Nguyen, V. N. D. Ta, K. A. Vu, T. D. Hua, T. N. T. Nguyen, T. Pham Duc, T. Trinh Van, B. L. Duong, P. M. Nguyen, , H. Chung The

This study examines the mucosal microbiome and Fusobacterium genomics in Vietnamese colorectal cancer patients, finding increased abundance of oral bacteria in tumors and genomic diversity within Fusobacterium species.

bioRxiv · Feb 25, 2022 · PreprintMicrobiology

Exploring the genomic diversity and antimicrobial susceptibility of Bifidobacterium pseudocatenulatum in the Vietnamese population to aid probiotic design

H. Chung The, C. Nguyen Ngoc Minh, C. Tran Thi Hong, T. Nguyen Thi Nguyen, L. J. Pike, C. Zellmer, T. Pham Duc, T.-A. Tran, T. Ha Thanh, M. Phan Van, G. Thwaites, M. A. Rabaa, L. J. Hall, S. Baker

The paper characterizes the genomic diversity and antimicrobial resistance of Bifidobacterium pseudocatenulatum in Vietnamese individuals to guide probiotic development.

bioRxiv · Apr 22, 2021Microbiology

Most-probable number based minimum duration of killing assay for determining the spectrum of rifampicin susceptibility in clinical M. tuberculosis isolates

S. Vijay, H. N. Nhung, N. L. H. Bao, D. D. A. Thu, L. P. T. Trieu, N. H. Phu, G. Thwaites, B. Javid, N. T. T. Thuong

This study introduces an MDK assay to quantify rifampicin susceptibility in M. tuberculosis isolates, showing variation in killing times and correlation with tolerant subpopulations.

Antimicrobial Agents and Chemotherapy · Feb 17, 2021Peer-reviewedMicrobiology

Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone

L. Whitworth, R. Troll, A. J. Pagan, F. Roca, P. H. Edelstein, M. Troll, D. Tobin, N. H. Phu, N. D. Bang, G. Thwaites, N. T. Thuong Thuong, R. Sewell, L. Ramakrishnan

The paper examines how pre-treatment CSF cytokine levels influence survival in dexamethasone-treated tuberculous meningitis, finding higher cytokine levels correlate with better survival.

bioRxiv · Nov 23, 2020Immunology

A novel method for measuring phenotypic colistin resistance in Escherichia coli populations from chicken flocks

N. T. Nguyen, N. T. Phuong Yen, N. V. Ky Thien, N. Van Cuong, B. T. Kiet, J. I. Campbell, G. Thwaites, S. Baker, R. B. Geskus, J. J. Carrique-Mas

This paper develops and validates a growth-based microdilution method to measure phenotypic colistin resistance in pooled E. coli populations from chicken flocks, finding higher resistance in flocks recently exposed to colistin.

bioRxiv · Oct 22, 2020Microbiology

Reducing antimicrobial usage in small-scale chicken farms in Vietnam: A three-year intervention study

D. H. Phu, N. V. Cuong, B. D. Truong, B. T. Kiet, V. B. Hien, H. T. V. Thu, L. K. Yen, N. T. T. Minh, P. Padungtod, E. Setyawan, G. Thwaites, J. Rushton, J. Carrique-Mas

This study shows that providing veterinary advice to small-scale chicken farms in Vietnam reduced antimicrobial use by 66% and mortality by 40% without harming flock health.

bioRxiv · Sep 13, 2020Microbiology

Effects of prophylactic and therapeutic antimicrobial uses in small-scale chicken flocks

V. C. Nguyen, T. K. Bach, H. P. Doan, T. B. V. Nguyen, B. H. Vo, G. Thwaites, J. CARRIQUE-MAS, M. Choisy

The paper examines the effects of prophylactic and therapeutic antimicrobial use on disease incidence and mortality in small-scale chicken flocks in Vietnam, finding that prophylactic use often increases disease risk while some therapeutic classes reduce mortality.

bioRxiv · Jul 2, 2020Pharmacology & Toxicology

Diagnostic Cerebrospinal Fluid Biomarker Discovery and Validation in Patients with Central Nervous System Infections

T. T. Thanh, C. Casals-Pascual, N. T. H. Ny, N. M. Ngoc, R. Geskus, L. N. T. Nhu, N. T. T. Hong, D. T. Duc, D. D. A. Thu, P. N. Uyen, V. B. Ngoc, L. T. M. Chau, V. X. Quynh, N. H. H. Hanh, N. T. T. Thuong, , L. V. Tan

This study identifies and validates lipocalin 2 (LCN2) as a sensitive and specific biomarker for bacterial meningitis in cerebrospinal fluid.

bioRxiv · Jan 13, 2020 · PreprintMicrobiology