L. J. Hall

Gut microbiota and faecal cytokine profiles of rural Cambodian infants and links to early life nutrition and diarrhoeal episodes.

This study examines gut microbiota and cytokine profiles in rural Cambodian infants, finding associations between breastfeeding, pathogen exposure, and microbial composition.

A hybrid and poly-polish workflow for the complete and accurate assembly of phage genomes: a case study of ten przondoviruses

This paper introduces HYPPA, a hybrid assembly workflow for phage genomes, demonstrating its ability to accurately assemble and correct phage genomes without laborious validation.

Maternal microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice

This study shows that Bifidobacterium breve UCC2003 in the maternal gut microbiota promotes placental development, nutrient transport, and fetal growth in mice.

Mucosal microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients

This study examines the mucosal microbiome and Fusobacterium genomics in Vietnamese colorectal cancer patients, finding increased abundance of oral bacteria in tumors and genomic diversity within Fusobacterium species.

A novel bacteriocin produced by Bifidobacterium longum subsp. infantis has dual antimicrobial and immunomodulatory activity

Dissemination and pathogenesis of toxigenic Clostridium perfringens strains linked to neonatal intensive care units and Necrotising Enterocolitis

This study identifies hypervirulent C. perfringens strains linked to NEC in preterm infants, showing their dissemination between hospitals and increased virulence.

Macrophage metabolism in the intestine is compartment-specific and regulated by the microbiota

This study shows that intestinal macrophage metabolism varies by gut compartment and is influenced by the microbiota, with colonic macrophages showing increased metabolic activity after antibiotic treatment.

Bifidobacterium castoris strains isolated from wild mice show evidence of frequent host switching and diverse carbohydrate metabolism potential

Exploring the genomic diversity and antimicrobial susceptibility of Bifidobacterium pseudocatenulatum in the Vietnamese population to aid probiotic design

The paper characterizes the genomic diversity and antimicrobial resistance of Bifidobacterium pseudocatenulatum in Vietnamese individuals to guide probiotic development.

Clostridium perfringenosum sp. nov., a closely related species toClostridium perfringens and its virulence factors, isolated from a humansoft tissue infection

This paper describes the discovery of a new Clostridium species, C. perfringenosum, closely related to C. perfringens, based on genomic and phenotypic analyses of isolates from a human infection.

Improved molecular characterization of the Klebsiella oxytoca complex reveals the prevalence of the kleboxymycin biosynthetic gene cluster

The paper reclassifies three Klebsiella strains as K. michiganensis and identifies the kleboxymycin BGC in multiple species of the K. oxytoca complex, highlighting its clinical relevance and need for inclusion in virulence databases.

Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence-associated factors

The paper isolates and characterizes Klebsiella species from preterm infants, revealing diverse species and antimicrobial resistance traits associated with health and disease.

Bifidobacterium breve UCC2003 exopolysaccharide modulates the early life microbiota by acting as a dietary substrate

This study shows that Bifidobacterium breve UCC2003 exopolysaccharide (EPS) alters infant microbiota and metabolite profiles by serving as a nutrient substrate.

Bifidobacterium breve UCC2003 induces a distinct global transcriptomic programme in neonatal murine intestinal epithelial cells

This study shows that Bifidobacterium breve UCC2003 significantly alters the transcriptome of neonatal intestinal epithelial cells, enhancing cell replication, differentiation, and growth.

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumour growth via a mast cell-dependent pathway

This study shows antibiotic-induced gut microbiota disturbances accelerate breast tumour growth in mice via mast cell-dependent mechanisms.

Succession of Bifidobacterium longum strains in response to the changing early-life nutritional environment reveals specific adaptations to distinct dietary substrates.

The paper investigates how Bifidobacterium longum strains adapt to changing infant diets through genomic and phenotypic analysis of strains from breast- and formula-fed infants.

Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome

This study shows that supplementing preterm infants with Bifidobacterium and Lactobacillus changes their gut microbiota and increases fecal acetate and lactate levels, resembling a full-term infant's gut environment.

The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding

This study shows that early life gut microbiota in mice prevents pathological small intestinal epithelial cell shedding, with antibiotic treatment reversing this protection.

Infant diet promotes Bifidobacterium community cooperation within a single ecosystem

The paper investigates how infant diet influences bifidobacterial community composition and cooperation in the gut, showing resource sharing enhances nutrient utilization and supports Bifidobacterium dominance.

Genomic analysis on broiler-associated Clostridium perfringens strains and caecal microbiome profiling reveals key factors linked to poultry Necrotic Enteritis

This study identifies hypervirulent Clostridium perfringens strains and microbiome changes associated with necrotic enteritis in broiler chickens.

Phylogenomic analysis of Clostridium perfringens identifies isogenic strains in gastroenteritis outbreaks, and novel virulence-related features

This study uses whole genome sequencing to analyze C. perfringens strains from gastroenteritis outbreaks, identifying isogenic strains and novel virulence features.

Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation

This study shows that antibiotics disrupt the gut microbiota, leading to faster breast tumour growth and metabolic changes in mice.