Author

G. Tosato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. Wang· 2 shared J.-X. Feng· 2 shared A. Abdelmaksoud· 1 shared A. D. Tran· 1 shared A. Turtoi· 1 shared C. C. Li· 1 shared E. Cornillot· 1 shared E. Turtoi· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

D. Wang

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Author profile →

3 papers

Recent·Most cited

Bone marrow hemogenic endothelial cells contribute multilineage hematopoietic progenitors in adult mice

J.-X. Feng, M.-T. Yang, C. C. Li, F. Livak, A. Abdelmaksoud, D. Wang, G. Tosato

The paper identifies a subset of bone marrow endothelial cells in adult mice that generate hematopoietic progenitors and mature blood cells through endothelial-to-hematopoietic transition.

bioRxiv · Sep 9, 2022 · PreprintCell Biology

Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth

Y. Wang, O. Salvucci, H. Ohnuki, A. D. Tran, T. Ha, J.-X. Feng, M. DiPrima, H. Kwak, D. Wang, M. Kruhlak, G. Tosato

This study shows that inhibiting SHP2 in endothelial cells reduces tumor growth by damaging the tumor vasculature, independent of SHP2 effects in tumor cells.

bioRxiv · Oct 6, 2020Cancer Biology

The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities

M. Alame, E. Cornillot, V. Cacheux, G. Tosato, M. Four, L. De Oliveira, S. Gofflot, P. Delvenne, E. Turtoi, S. Cabello-Aguilar, M. Nishiyama, A. Turtoi, V. Costes Martineau, J. Colinge

This study characterizes the molecular landscape and microenvironment of salivary duct carcinoma, identifying immune checkpoints and stromal features that suggest new therapeutic strategies.

bioRxiv · Oct 21, 2019Cancer Biology