Author

G. Trigo-Gonzalez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. G. Huntsman· 2 shared M. Hirst· 2 shared A. Carles· 1 shared A. Shanks· 1 shared E. Su· 1 shared F. Kalantari· 1 shared G. B. Morin· 1 shared J. P. Wells· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

D. G. Huntsman

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2 papers

Recent·Most cited

Genome-wide CRISPR screen identifies KEAP1 perturbation as a vulnerability of ARID1A-deficient cells

L.-A. Fournier, F. Kalantari, J. P. Wells, J. S. Lee, G. Trigo-Gonzalez, M. M. Moksa, T. Smith, J. White, A. Shanks, L. Wang, E. Su, Y. Wang, D. G. Huntsman, M. Hirst, P. C. Stirling

The paper identifies KEAP1 as a genetic dependency in ARID1A-deficient clear cell ovarian carcinoma cells through a genome-wide CRISPR screen, showing KEAP1 perturbation leads to growth inhibition.

bioRxiv · Nov 14, 2023Cancer Biology

The pathognomonic FOXL2 C134W mutation alters DNA binding specificity

A. Carles, G. Trigo-Gonzalez, R. Cao, S.- W. G. Cheng, M. Moksa, M. Bilenky, G. B. Morin, D. G. Huntsman, M. Hirst

This study investigates the molecular effects of the FOXL2 C134W mutation in AGCT by analyzing DNA binding and transcriptome changes in engineered cell lines.

bioRxiv · Mar 20, 2020Cancer Biology