Author

G.-R. Hwang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Fesler· 4 shared J. Ju· 4 shared J. G. Yuen· 3 shared A. Ojha· 1 shared A. Pal· 1 shared E. Intriago· 1 shared H. Farley· 1 shared H. Wang· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersCancer Biology

A. Fesler

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4 papers

Recent·Most cited

Development of Gemcitabine-Modified miRNA Mimics as Cancer Therapeutics for Pancreatic Ductal Adenocarcinoma

J. G. Yuen, G.-R. Hwang, A. Fesler, E. Intriago, A. Pal, A. Ojha, J. Ju

Yuen and Hwang et al. developed Gem-modified miRNA mimics that show enhanced efficacy in inhibiting PDAC cell growth and tumor progression with reduced toxicity.

bioRxiv · Aug 14, 2023Cancer Biology

Development of a 5-FU Modified miR-129 Mimic as a Therapeutic for Non-Small Cell Lung Cancer

G.-R. Hwang, J. G. Yuen, A. Fesler, H. Farley, J. D. Haley, J. Ju

This study develops a 5-FU modified miR-129 mimic that inhibits NSCLC proliferation, induces apoptosis, overcomes drug resistance, and extends survival in vivo without toxicity.

bioRxiv · Sep 16, 2022Cancer Biology

Development of 5-FU-modified tumor suppressor microRNAs as a platform for novel microRNA-based cancer therapeutics

J. G. Yuen, A. Fesler, G.-R. Hwang, L.-B. Chen, J. Ju

This paper develops 5-FU-modified tumor suppressor miRNAs as a platform for cancer therapeutics, showing increased potency and delivery capability without delivery vehicles.

bioRxiv · Jun 23, 2022Cancer Biology

Functional significance and therapeutic potential of miR-15a mimic in pancreatic ductal adenocarcinoma

S. Guo, A. Fesler, W. Huang, Y. Wang, J. Yang, X. Wang, Y. Zheng, G.-R. Hwang, H. Wang, J. Ju

This study shows that miR-15a mimic, especially modified with 5-FU, reduces PDAC cell proliferation and tumor growth, suggesting its therapeutic potential and prognostic value.

bioRxiv · Jul 28, 2019Cancer Biology