DRP1 depletion protects NK cells against hypoxia-induced dysfunction
Tias Verhezen, Astrid Van den Eynde, Peter Verstraelen, Laura Gehrcken, Gabriele Palmiotto, Ho Wa Lau, Winnok Harald De Vos, Sanne van der Heijden, Louize Brants, Jöran Melis, Jonas R.M. Van Audenaerde, Steven Van Laere, Filip Lardon, Christophe Deben, An Wouters, , Jorrit De Waele
This study shows that DRP1 depletion protects NK cells from hypoxia-induced dysfunction by preserving mitochondrial function and cytotoxic activity.
bioRxiv · Jun 23, 2025 · PreprintImmunology