Proteo-transcriptomics and morphometrics of teleost cardiac cells define regulatory networks and exercise-induced cardiomyocyte hypertrophy and hyperplasia
Osvaldo Contreras, Gabrielle D Smith, Celine Santiago, Moumitha Dey, Chris G. Thekkedam, Renee Chand, Álvaro González-Rajal, Ling Zhong, John George Lock, Emily S. W. Wong, Diane Fatkin, Richard Paul Harvey
The paper develops a workflow for isolating and profiling adult teleost cardiac cells, revealing exercise-induced hypertrophy and hyperplasia and defining proteo-transcriptomic regulatory networks.
bioRxiv · Jan 12, 2026 · PreprintSystems Biology