Author

Chris G. Thekkedam

Victor Chang Cardiac Research InstituteORCID 0000-0002-3106-5080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:zebrafish· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Osvaldo ContrerasiD· 3 shared Richard Paul HarveyiD· 3 shared Álvaro González-RajaliD· 1 shared Amy M. NicksiD· 1 shared Anai Gonzalez-CorderoiD· 1 shared Celine SantiagoiD· 1 shared David T. HumphreysiD· 1 shared Diane FatkiniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenomics

Osvaldo ContrerasORCID

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3 papers

Recent·Most cited

GenomicsComputational and Structural Biotechnology JournalPeer-reviewedMar 1, 2026

A scalable MNase-seq framework for reproducible nucleosome profiling across pluripotent stem cell and cardiomyocyte models

Chris G. Thekkedam, David T. Humphreys, Marina Naval-Sánchez…·Osvaldo Contreras

The paper develops a scalable MNase-seq workflow for reproducible nucleosome profiling across multiple cell types and models.

DOI 10.34133/csbj.0204

𝕏 PostBluesky

Systems BiologybioRxivPreprintJan 12, 2026

Proteo-transcriptomics and morphometrics of teleost cardiac cells define regulatory networks and exercise-induced cardiomyocyte hypertrophy and hyperplasia

Osvaldo Contreras, Gabrielle D Smith, Celine Santiago…·Richard Paul Harvey

The paper develops a workflow for isolating and profiling adult teleost cardiac cells, revealing exercise-induced hypertrophy and hyperplasia and defining proteo-transcriptomic regulatory networks.

DOI 10.64898/2026.01.11.698907

zebrafishproteomics

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Developmental BiologyiSciencePeer-reviewedAug 18, 2025

OpenEMMU: a versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamics

Osvaldo Contreras, Chris G. Thekkedam, John James Zaunders…·Richard Paul Harvey

OpenEMMU improves EdU staining efficiency, brightness, and multiplexing for DNA replication and cell cycle analysis using affordable, open-source reagents.

8 citations

zebrafishimaging

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