Author

Garrett T. Wong

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 5 Assay:bulk RNA-seq· 4 Research Focus:GWAS / association mapping· 3 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Jack HumphreyiD· 3 shared Towfique RajiD· 3 shared Vahram H. HaroutunianiD· 2 shared Yang LiiD· 2 shared A Baker· 1 shared A Robbins· 1 shared A Spurkland· 1 shared Aaron Brandes· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersGenomics

Jack HumphreyORCID

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Author profile →

5 papers

Recent·Most cited

Environmental challenge rewires functional connections among human genes

Benjamin W. Herken, Garrett T. Wong, Thomas M. Norman, Luke A. Gilbert

The paper quantifies how human gene functional connections change under environmental stress, revealing large-scale rewiring of genetic interactions across different conditions.

bioRxiv · Aug 9, 2023 · PreprintGenomics

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Kurt W. Farrell, SoongHo Kim, Natalia Han, Megan A. Iida, Elias M. Gonzalez, Marcos Otero‐García, Jamie M. Walker, Timothy E. Richardson, Alan Edward Renton, Shea J. Andrews, Brian Fulton‐Howard, Jack Humphrey, Ricardo A. Vialle, Kathryn R. Bowles, Kátia de Paiva Lopes, , John F. Crary

This study identifies JADE1 as a novel genetic factor in tauopathy through genome-wide association and functional validation in human and Drosophila models.

Acta Neuropathologica · Oct 31, 2021Peer-reviewedNeuroscience

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

Nikolaos A. Patsopoulos, Sergio E. Baranzini, Adam Santaniello, Parisa Shooshtari, Chris J. Cotsapas, Garrett T. Wong, Ashley Harris Beecham, Tojo James, Joseph M. Replogle, Ioannis S. Vlachos, Cristin Aubin, Tune H. Pers, Aaron Brandes, Charles C. White, Brendan T Keenan, , John W. Thorpe

The paper reports a detailed genetic and genomic map of multiple sclerosis, identifying susceptibility genes in peripheral immune cells and brain-resident microglia.

Science · Sep 26, 2019Peer-reviewedGenetics

Prioritizing Parkinson’s Disease genes using population-scale transcriptomic data

Yang Li, Garrett T. Wong, Jack Humphrey, Towfique Raj

This study prioritizes Parkinson’s Disease genes using transcriptomic data, identifying 29 peripheral monocyte and 44 prefrontal cortex gene associations, including novel and known genes like MAPT.

Nature Communications · Mar 1, 2019Peer-reviewedGenomics

Integrative analyses of splicing in the aging brain: role in susceptibility to Alzheimer’s Disease

Towfique Raj, Yang Li, Garrett T. Wong, Jack Humphrey, Minghui Wang, Satesh Ramdhani, Ying‐Chih Wang, Bernard Ng, Ishaan Gupta, Vahram H. Haroutunian, Eric E. Schadt, Tracy L. Young‐Pearse, Sara Mostafavi, Bin Zhang, Pamela B. Sklar, , Philip L. De Jager

This study identifies splicing variations in aging brains linked to Alzheimer’s Disease, finds genetic regulation of splicing, and highlights shared pathways with other neurodegenerative diseases.

Nature Genetics · Sep 28, 2018Peer-reviewedGenomics