Author

Gaurab K. Sarangi

Max Planck Institute for Evolutionary Anthropology

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

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Aida M. AndrésiD· 1 shared Baldomero OlivaiD· 1 shared Elias S.J. ArnériD· 1 shared Jasmin ReesiD· 1 shared Jordi Villà-FreixaiD· 1 shared Martin FlooriD· 1 shared Qing ChengiD· 1 shared Sergi CastellanoiD· 1 shared

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1 paper

Recent·Most cited

Molecular BiologyGenome Biology and EvolutionPeer-reviewedMar 1, 2024

Ancient loss of catalytic selenocysteine spurred convergent adaptation in a mammalian oxidoreductase

Jasmin Rees, Gaurab K. Sarangi, Qing Cheng…·Sergi Castellano

The paper reconstructs and assays ancient enzymes to show that losing selenocysteine in GPX6 led to functional loss and convergent evolution in mammalian oxidoreductases.

1 citation

mousehuman

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