Martin Floor

The paper identifies improved hydroxymethylfurfural oxidases through iterative computational methods combining molecular simulation and machine learning.

This paper improves an enzyme's thermostability and cofactor compatibility through multi-objective engineering, achieving variants with better heat resistance and higher cofactor activity retention.

The paper reconstructs and assays ancient enzymes to show that losing selenocysteine in GPX6 led to functional loss and convergent evolution in mammalian oxidoreductases.

The paper shows that phosphorylated IκB binds chromatin via acetylated H4 and that proteolytic cleavage of H4 inhibits this binding, affecting intestinal cell differentiation.