Broad transcriptomic dysregulation across the cerebral cortex in ASD
Jillian R. Haney, Brie Wamsley, George T Chen, Sepideh Parhami, Prashant S. Emani, Nathan Chang, Gil D. Hoftman, Diego de Alba, Gaurav Prashant Kale, Gokul Ramaswami, Christopher Hartl, Ting Jin, Daifeng Wang, Jing Ou, Ye Emily Wu, , Daniel H. Geschwind
The paper identifies widespread transcriptomic dysregulation across multiple cortical regions in ASD, showing regional variation and genetic enrichment in synaptic and protein folding genes.
bioRxiv · Dec 17, 2020 · PreprintNeuroscience