Widespread remodeling of the RNA editome underlies transcriptional and clinical heterogeneity in pediatric acute lymphoblastic leukemia
Sara Brin Rosenthal, Thomas C. Whisenant, Roman Šášik, Maria Rivera, Geena Il Defonso, Charles-Alexandre Roy, Sabina Enlund, Rawan Shraim, Kathleen M Fisch, David T. Teachey, Frida Holm, Dennis John Kuo, Qingfei Jiang
The paper identifies widespread RNA editing changes in pediatric ALL, linking them to clinical outcomes and potential therapeutic targets.
bioRxiv · Dec 6, 2025 · PreprintCancer Biology