Author

Roman Šášik

University of California San DiegoORCID 0000-0002-9266-8993Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Kathleen M FischiD· 2 shared Sara Brin RosenthaliD· 2 shared Alison G. BarberiD· 1 shared Balaji Raao· 1 shared Carla F. KimiD· 1 shared Charles-Alexandre Roy· 1 shared Cynthia M QuinteroiD· 1 shared David A. Bennett· 1 shared

Activity by Year

2018-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

Kathleen M FischORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Widespread remodeling of the RNA editome underlies transcriptional and clinical heterogeneity in pediatric acute lymphoblastic leukemia

Sara Brin Rosenthal, Thomas C. Whisenant, Roman Šášik, Maria Rivera, Geena Il Defonso, Charles-Alexandre Roy, Sabina Enlund, Rawan Shraim, Kathleen M Fisch, David T. Teachey, Frida Holm, Dennis John Kuo, Qingfei Jiang

The paper identifies widespread RNA editing changes in pediatric ALL, linking them to clinical outcomes and potential therapeutic targets.

bioRxiv · Dec 6, 2025 · PreprintCancer Biology

Smed-pou4-2 regulates mechanosensory neuron regeneration and function in planarians

Ryan A McCubbin, Mohammad A Auwal, Shengzhou Wang, Sarai Alvarez Zepeda, Roman Šášik, Robert W. Zeller, Kelly G. Ross, Ricardo M. Zayas

This study identifies Smed-pou4-2 as a regulator of mechanosensory neuron regeneration and function in planarians, showing its role in maintaining sensory identity and behavior.

eLife · Nov 18, 2025Peer-reviewedDevelopmental Biology

Regulation of lung cancer initiation and progression by the stem cell determinant Musashi

Alison G. Barber, Cynthia M Quintero, Michael Hamilton, Nirakar Rajbhandari, Roman Šášik, Yan Zhang, Carla F. Kim, Hatim Husain, Xin Sun, Tannishtha Reya

This study identifies Msi2 as a key regulator in lung cancer initiation and progression, showing its dual role in sensitizing cells to transformation and driving tumor growth.

eLife · Mar 6, 2025Peer-reviewedCancer Biology

Perturbed functional networks in Alzheimers Disease reveal opposing roles for TGIF and EGR3

Saranya Canchi, Balaji Raao, Deborah Masliah, Sara Brin Rosenthal, Roman Šášik, Kathleen M Fisch, Philip L. De Jager, David A. Bennett, Robert A. Rissman

The paper identifies TGIF1 and EGR3 as master regulators in Alzheimer's Disease by integrating gene expression and protein interactions, revealing their opposing roles in neuroprotection and synaptic deficits.

bioRxiv · Mar 22, 2018 · PreprintBioinformatics