Thomas C. Whisenant

Loss of the rhomboid protease Rhbdl2 in zebrafish larvae speeds tail fin regrowth after injury, raises macrophage accumulation and Rac2 protein, and Rac2 knockdown reverses both effects.

This study shows Derlin-mediated ERAD of ORMDL3 prevents mitochondrial dysfunction by maintaining sphingolipid homeostasis and ER-mitochondria contact sites.

The paper identifies widespread RNA editing changes in pediatric ALL, linking them to clinical outcomes and potential therapeutic targets.

This study shows that neuronal activity increases mitochondrial O-GlcNAcylation, which helps neurons meet energy demands based on fuel availability.