Author
Children's Hospital of PhiladelphiaORCID 0000-0001-7373-8987Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Nadezhda V. Terekhanova, Xiaolong Chen, Kin-Hoe Chow…·Jinghui Zhang
The paper identifies non-coding somatic variants in TAL1 regulatory regions that reactivate enhancers normally active in hematopoietic stem cells in T-lineage acute lymphoblastic leukemia.
Alberto Carturan, Mathew G. Angelos, Puneeth Guruprasad…·Marco Ruella
This paper develops anti-CD2 CAR T-cells that overcome fratricide and improve efficacy by incorporating a PD-1:CD2 switch receptor to restore CD2 signaling.
Sara Brin Rosenthal, Thomas C. Whisenant, Roman Šášik…·Qingfei Jiang
The paper identifies widespread RNA editing changes in pediatric ALL, linking them to clinical outcomes and potential therapeutic targets.
Zhenhua Li, Wenjian Yang, Gang Wu…·Jun J Yang
The paper maps human DNA replication origins using whole-genome sequencing data, identifying a 16 bp motif and periodicity, and links replication activity to gene expression and genetic variation.
Anna Eames Seffernick, Xueyuan Cao, Cheng Cheng…·Stanley B Pounds
BEAM integrates multiple omics profiles with multiple clinical outcomes using bootstrap resampling to identify significant associations, outperforming existing methods in simulations and a pediatric leukemia application.